The City of Dis was the infernal city that made the sixth circle of Hell and the lower circles below up. Inside Heresy are the heretics and pagans who laid in the fiery tombs. Throughout the city are the Dark Priests who worshiped their dark god. Dante reached the gates of the city by controlling the boatman named Phlegyas and used his great strength to smash the gates of the city down. Once he was inside, Dante must battle his way through the fiery tombs and corridors of the hellish fortress if he was to reach the seventh circle beyond.
- In "The Inferno", Dante and Virgil arrived at the gates of the City of Dis after crossing the fifth circle. The walls of the city encompassed the sixth circle of Hell and the other circles below. The gates are guarded by the Fallen Angels, the Furies and Medusa who threatened Dante and Virgil and refused them access. An angel of God ultimately descends to allow them passage into the city, destroying one of the walls.
- The quote that Dante makes while moving towards the City of Dis is modeled after the narrative in Canto IX of the original poem.
- In Greco-Roman mythology, "Dis" or "Dis Pater" was a euphemistic name for the god Pluto (Hades). "Dis" is derived from the word "Deus" or "Theos", which meant "God" and was used due to the superstition that calling Hades by his true name would bring him to you (Equated with asking Death itself to come and take you to the Underworld).